Figure 4.

Phylogenetic trees of selected phage proteins. (a) Analysis of large terminase subunits using proteins from phages of well-known packaging mechanisms. (b) Analysis of the tubulin spindle protein of phage ϕKp24 and all protein homologues to the tubulin spindle of phage 201phi2-1 found by psi-Blast and Hmmer. (c) Analysis of the nucleus shell protein of phage ϕKp24 and all protein homologues to the nucleus shell protein of phage 201phi2-1 found by psi-Blast and Hmmer. Trees were built from MAFFT alignments using RAxML with bootstrapping of 100. Identical colours were used in panels (b) and (c) to identify similar phage clusters. All phages in panels (b) and (c) have genomes above 200 kb (Jumbo phages) with the exception of those marked with *, which have a genome size of 167–197 kb.