Figure 2.

The Composition of the Infant Gut Microbiota at 1-Month of Age was Associated with Infant Growth in the First Year of Life

Figure 2. (a) Comparison of the adjusted abundances of features associated with rapid- and non-rapid growth. The abundances were adjusted by taking the log-ratio of the top- and bottom 40% of features ranked based on their log-fold change with respect to rapid growth from our multinomial regression model. Selected features were additionally curated to exclude taxa not assigned to at least the genus level, and those assigned to genera present in both numerator (i.e., rapid growth) and denominator (i.e., non-rapid growth) groups. After curation, there were 25 and 27 features in numerator (i.e., rapid growth) and denominator (i.e., non-rapid growth) groups, respectively. Based on this selection, 110 of the 132 samples were included (83.3%). The multinomial regression model was additive, and adjusted for birth weight, birth length, and Faith’s PD. (b) The curated selection of the top- and bottom 40% of features (sOTU) grouped at the genus-level that were associated with infant growth. Taxa shared between groups are those excluded during curation in (A).