Table 2.

In vitro evaluation results of IC₅₀ values for growth of L. donovani promastigotes

Compound	Acyl Chain	IC50 ± SD (µM)a	Compound	Acyl chain	IC50 ± SD (µM)a
1a	Palmitoyl	52.59 ± 1.44	2a	Palmitoyl	54.61 ± 2.02
1b	Palmitoleoyl	66.13 ± 3.61	2d	Erucoyl	>100
1d	Erucoyl	46.65 ± 0.45	3a	Palmitoyl	>100
1e	Palmitoyl	28.32 ± 1.38	3c	Oleoyl	>100
1g	Erucoyl	68.47 ± 0.04	3d	Erucoyl	>100
Erufosine	–	9.75 ± 2.41	Miltefosine	–	4.94 ± 0.47

^aConcentration was calculated from the dose response curves that inhibit the growth of L. donovani promastigotes by 50% after incubation for 3 days, relative to control.