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In vivo acute toxicity evaluation. (A) Body weight of ICR mice (g) ‒ measurement time point (day, **p < 0.01); (B) ALT activity at 8, 22 and 36 h after single dosing (control) or A10; (C) AST activity at 8, 22 and 36 h after single dosing (control) or A10; (D) Histomorphological observation of mouse liver treated with A10 vector (control); The HE-stained field was 100 µM.
