Table 2. Clinical characteristics of notified cases of invasive listeriosis, Germany, 2010–2019*.
| Characteristic | Pregnancy-associated, no. (%) cases | Non–pregnancy-associated, no. (%) cases |
|||
|---|---|---|---|---|---|
| Children/adolescents <18 y | Adults 18–64 y | Adults ≥65 y | Total | ||
| Total |
301 (100) |
37 (100) |
1,172 (100) |
3,855 (100) |
5,064 (100) |
| Sex | |||||
| F | 301 (100) | 22 (59) | 437 (37) | 1,573 (41) | 2,032 (40) |
| M |
0 |
|
|
|
|
| Isolate source† | |||||
| Cerebrospinal fluid | 6 (2) | 21 (57) | 277 (24) | 359 (9) | 657 (13) |
| Blood | 152 (50) | 15 (41) | 800 (68) | 3,282 (85) | 4,097 (81) |
| Other sterile site | NA | 1 (3) | 87 (7) | 186 (5) | 274 (5) |
| Birth setting‡ |
162 (54) |
NA |
NA |
NA |
NA |
| Severity | |||||
| Hospitalization§ | 253 (84) | 36 (97) | 1,064 (95) | 3,535 (95) | 4,635 (92) |
| Death or fetal loss¶ | 58 (19) | 0# (0) | 113# (10) | 545# (14) | 658# (13) |
*NA, not applicable †When Listeria monocytogenes is isolated from multiple anatomic sites, only a single site is reported (priority order: cerebral spinal fluid, blood, other sterile site, and birth setting). ‡Either from a newborn, fetus, stillborn or from maternal tissue (placental tissue, uterus, cervix). §Hospitalizations among singleton neonates for 224 pregnancy-associated cases. ¶26 neonatal deaths, 32 fetal losses. Among all pregnancy-associated cases 161 premature births were recorded. #Information available for 4,989/5,064 (99%) of notified cases.