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. 2021 Sep;27(9):2349–2359. doi: 10.3201/eid2709.210934

Table 2. Multivariate analysis of factors predicting death at 6 weeks among patients with mucormycosis, India*.

Variables Survivors, n = 177 Non-survivors, n = 110 Odds ratio (95% CI) p value
Mean age, y (SD)
52.6 (15.1)
54.7 (14.0)
1.02 (1.00–1.04)
0.03
Underlying disease
None 10 (5.6) 9 (8.2) Referent Referent
   Isolated COVID-19 42 (23.7) 19 (17.3) 0.56 (0.17–1.83) 0.34
   Diabetes mellitus 109 (61.6) 71 (64.5) 0.92 (0.32–2.64) 0.88
   Traumatic inoculation 8 (4.5) 4 (3.6) 1.30 (0.25–6.80) 0.76
   Others 5 (2.8) 3 (2.7) 1.20 (0.18–7.81) 0.85
   Renal transplantation 1 (0.6) 2 (1.8) 6.87 (0.42–113.19) 0.18
   Hematological malignancy
2 (1.1)
2 (1.8)
1.60 (0.14–18.72)
0.71
Site of involvement
   Rhino-orbital 117 (66.1) 50 (45.5) Referent Referent
   Rhino-orbito-cerebral 39 (22) 39 (35.5) 2.39 (1.30–4.40) 0.005
   Pulmonary 8 (4.5) 14 (12.7) 3.26 (1.05–10.11) 0.04
   Other†
13 (7.3)
7 (6.4)
1.29 (0.43–3.86)
0.64
Admission to the intensive care unit
32 (18.1)
35 (31.8)
2.87 (1.43–5.75)
0.003
Combined medical surgical therapy
135 (76.3)
69 (62.7)
0.77 (0.41–1.45)
0.41
Combination of antifungals
   Single antifungal drug 95 (53.7) 88 (80) Referent Referent
   Concurrent 9 (5.1) 5 (4.5) 0.37 (0.09–1.44) 0.15
   Sequential 73 (41.2) 17 (15.5) 0.17 (0.87–0.35) 0.0001

*Values are no. (%) except as indicated. Bold text indicates statistical significance. COVID-19, coronavirus disease. †Includes cutaneous, stomach, disseminated, or other.