Table 2.
Relative risk of fracture for frail women across time frames of 1, 2, and 5 years based on being frail at (A) age 75 and (B) age 80
| 1-year risk | 2-year risk | 5-year risk | ||||
|---|---|---|---|---|---|---|
| SHRa | 95% CI | SHR | 95% CI | SHR | 95% CI | |
| (A) Frail at age 75 | ||||||
| Any | 1.55 | (0.87–2.76) | 1.70 | (1.11–2.60) | 1.38 | (1.02–1.86) |
| Major osteoporotic | 1.71 | (0.90–3.25) | 1.89 | (1.17–3.06) | 1.38 | (0.99–1.93) |
| Hip | 3.94 | (1.20–12.9) | 3.04 | (1.34–6.88) | 2.03 | (1.13–3.63) |
| Vertebral | 1.19 | (0.38–3.74) | 1.88 | (0.79–4.46) | 1.83 | (1.10–3.04) |
| (B) Frail at age 80 | ||||||
| Any | 1.85 | (0.95–3.59) | 1.59 | (1.02–2.48) | 1.52 | (1.13–2.04) |
| Major osteoporotic | 1.89 | (0.93–3.83) | 1.79 | (1.12–2.86) | 1.53 | (1.12–2.09) |
| Hip | 5.43 | (1.13–26.2) | 2.0 | (0.91–4.39) | 1.48 | (0.90–2.44) |
| Vertebral | 1.86 | (0.57–6.09) | 1.43 | (0.63–3.24) | 1.97 | (1.21–3.21) |
aSubdistribution hazard ratios with reference category nonfrail. Frailty status was assessed at beginning of each period calculated (ages 75 and 80)