Table 2.
Diagnostic values and observer agreement for predicting the histology of superficial Barrett’s esophagus-related neoplasms
| General diagnosisa (n, reviewers’ assessments) | Sensitivity (95% CI) | Specificity (95% CI) | Accuracy (95% CI) | PPV (95% CI) | NPV (95% CI) | Inter-observer agreements, κ value (95% CI) | Intra-observer agreements, κ value (95% CI) |
|---|---|---|---|---|---|---|---|
| Overall (n = 1560) | 87 (85–89) | 97 (96–99) | 91 (90–93) | 98 (97–99) | 83 (81–86) | 0.77 (0.75–0.80) | 0.83 (0.80–0.86) |
| Experts (n = 780) | 87 (84–90) | 98 (96–99) | 91 (89–93) | 98 (97–99) | 83 (80–86) | 0.75 (0.70–0.80) | 0.83 (0.79–0.87) |
| Non-experts (n = 780) | 87 (84–91) | 97 (96–99) | 91 (89–93) | 98 (96–99) | 84 (80–87) | 0.79 (0.74–0.84) | 0.83 (0.80–0.87) |
PPV positive predictive value, NPV negative predictive value, CI confidence interval
aGeneral diagnosis and predicted histology based on mucosal plus vascular pattern