Table 3.
Fatal and nonfatal acute coronary heart disease events.
| hsCRP | TG:HDL-C Ratio | Number of individuals (%) | Hazard RatioUn-adjusted | Hazard RatioAdjusted* |
|---|---|---|---|---|
| Low | Low | 6112 (29.2%) 4856 (23.2%) 4417 (21.0%) 5569 (26.6%) |
1.00 (Reference) | 1.00 (Reference) |
| High | Low | 1.56 (1.33, 1.85) | 1.57 (1.33, 1.86) | |
| Low | High | 1.55 (1.31, 1.83) | 1.28 (1.08, 1.52) | |
| High | High | 2.03 (1.74, 2.37) | 1.69 (1.44, 1.99) | |
| Observations | 20,954 | 20,954 | 20,954 | |
| Measures of Interaction in the Additive Scale | Un-adjusted | Adjusted | ||
| Excess Risk due to Interaction (RERI) Attributable Proportion (AP) Synergy Index (SI) |
−0.08 (−0.42, 0.26) | −0.18 (−0.50, 0.13) | ||
| −0.04 (−0.21, 0.13) | −0.11 (−0.30, 0.08) | |||
| 0.93 (0.68, 1.23) | 0.77 (0.53, 1.14) | |||
| hsCRP | TG:HDL-C Ratio | Number of individuals (%) | Hazard RatioUn-adjusted | Hazard RatioAdjusted* |
|---|---|---|---|---|
| Low | Low | 6112 (29.2%) 4856 (23.2%) 4417 (21.0%) 5569 (26.6%) |
1.00 (Reference) | 1.00 (Reference) |
| High | Low | 1.56 (1.33, 1.85) | 1.57 (1.33, 1.86) | |
| Low | High | 1.55 (1.31, 1.83) | 1.28 (1.08, 1.52) | |
| High | High | 2.03 (1.74, 2.37) | 1.69 (1.44, 1.99) | |
| Observations | 20,954 | 20,954 | 20,954 | |
| Measures of Interaction in the Additive Scale | Un-adjusted | Adjusted | ||
| Excess Risk due to Interaction (RERI) Attributable Proportion (AP) Synergy Index (SI) |
−0.08 (−0.42, 0.26) | −0.18 (−0.50, 0.13) | ||
| −0.04 (−0.21, 0.13) | −0.11 (−0.30, 0.08) | |||
| 0.93 (0.68, 1.23) | 0.77 (0.53, 1.14) | |||
*Model adjusted for race, sex, age, income, education, smoking status, hypertension, use of aspirin, BMI category, and diabetes status. Total events include fatal, and nonfatal Acute Coronary Heart Disease (CHD) events.