TABLE 5.

Kinds and locations of unequivocally independent point mutations induced in the lacZα gene during replication of UV-irradiated M13mp2-oriR by XP variant cell extracts^a

Mutant	Position(s)	Mutation	Photoproduct context (5′→3′)c	Strandb
XR1	96	C · G→A · T	AAACCCTGG	Leading
XR4	96	C · G→A · T	AAACCCTGG	Leading
XR3	108	C · G→A · T	TACCCAACT	Leading
XR5	120	C · G→A · T	TCGCCTTGC	Leading
XR9	−57	C · G→T · A	AGCTCACTC	Lagging
XR11	−57	C · G→T · A	ACGTCACTC	Lagging
XR6	88	C · G→T · A	TTTCCCAGT	Lagging
XR8	88	C · G→T · A	TTTCCCAGT	Lagging
XR15	89	C · G→T · A	TTTCCCAGT	Lagging
XR7	90	C · G→T · A	TTTCCCAGT	Lagging
XR12	54	T · A→A · T	GAATTCGTA	Lagging
XR13	56	T · A→A · T	CGAATTCAC	Leading
XR10	70	T · A→A · T	GTCGTTTTA	Leading
XU14	132–136	ΔC	CATCCCCCT	Leading

^aThe target genes from 28 mutants derived with XP variant cell extracts were sequenced. Of these, six had no mutation in the target gene. Two had background mutations and were omitted from the analysis. 

^bStrand, as in Table 3. 

^cThe site of the mutation is underlined.