Table 1.
Demographics and Clinical Characteristics of the Training and Test Cohorts
| Variables | Training Cohort (n = 489) | Test Cohort (n = 209) | P-value | |||
|---|---|---|---|---|---|---|
| Demographic characteristics | ||||||
| Sex, n (%) | 0.583 | |||||
| Female | 22 (25) | 57 (27) | ||||
| Male | 367 (75) | 152 (73) | ||||
| Age, y | 64.0 (52.0, 74.0) | 63.0 (53.0, 72.0) | 0.216 | |||
| Smoking, n (%) | 314 (64) | 132 (63) | 0.857 | |||
| Weekend on admission, n (%) | 122 (25) | 69 (33) | 0.036 | |||
| Delay, n (%) | 119 (24) | 50 (24) | 0.984 | |||
| Vascular risk factors | ||||||
| Hypertension, n (%) | 297 (61) | 114 (55) | 0.15 | |||
| Diabetes mellitus, n (%) | 98 (20) | 45 (22) | 0.731 | |||
| Prior-Stroke, n (%) | 30 (6) | 8 (4) | 0.294 | |||
| CKD, n (%) | 107 (22) | 45 (22) | 0.998 | |||
| OHCA, n (%) | 44 (9) | 13 (6) | 0.282 | |||
| GRACE, score | 128.0 (105.0, 154.0) | 122.0 (102.0, 154.0) | 0.363 | |||
| Clinical data | ||||||
| HR, beats/min | 80.0 (73.0, 92.0) | 84.0 (72.0, 94.0) | 0.294 | |||
| SBP, mmHg | 126.0 (108.0, 140.0) | 126.0 (110.0, 141.0) | 0.4 | |||
| DBP, mmHg | 80.00 (72.00, 90.00) | 80.00 (68.00, 90.00) | 0.409 | |||
| Shock index | 0.7 (0.6, 0.8) | 0.6 (0.5, 0.8) | 0.965 | |||
| Killip, n (%) | 0.238 | |||||
| 1 | 369 (75) | 161 (77) | ||||
| 2 | 54 (11) | 16 (8) | ||||
| 3 | 23 (5) | 16 (8) | ||||
| 4 | 43 (9) | 16 (8) | ||||
| Laboratory examinations on admission | ||||||
| WBC, *109/L | 11.4 (8.6, 14.2) | 11.3 (8.6, 14.0) | 0.864 | |||
| Neutrophil count, *109/L | 8.9 (6.3, 11.8) | 9.1 (6.1, 11.5) | 0.898 | |||
| NLR | 6.8 (4.0, 10.7) | 6.3 (3.5, 10.9) | 0.735 | |||
| PLR | 152.4 (105.8, 228.7) | 148.4 (100.5, 218.4) | 0.325 | |||
| MLR | 0.5 (0.3, 0.8) | 0.5 (0.4, 0.8) | 0.28 | |||
| SIRI | 4.5 (2.6, 8.4) | 3.9 (2.5, 7.4) | 0.296 | |||
| SII | 1312.4 (789.4, 2256.4) | 1307.8 (678.1, 2247.2) | 0.545 | |||
| HB, g/L | 136.0 (121.0, 152.0) | 139.0 (120.0, 152.0) | 0.935 | |||
| RBC, *1012/L | 4.5 (3.9, 5.0) | 4.5 (4.0, 5.0) | 0.504 | |||
| PLT, *109/L | 208.0 (165.0, 256.0) | 212.0 (162.0, 248.0) | 0.566 | |||
| ALT, U/L | 31.0 (22.0, 52.0) | 34.0 (23.0, 56.0) | 0.175 | |||
| AST, U/L | 69.0 (36.0, 163.0) | 72.0 (34.0, 173.0) | 0.647 | |||
| GGT, U/L | 42.0 (25.0, 73.0) | 46.0 (29.0, 75.0) | 0.197 | |||
| BUN, mmol/L | 6.7 (5.2, 9.1) | 6.5 (5.2, 9.2) | 0.379 | |||
| Creatinine, umol/L | 99.0 (80.0, 124.0) | 97.0 (77.0, 123.0) | 0.317 | |||
| Uuric acid, umol/L | 472.0 (437.0, 537.0) | 473.0 (436.0, 523.0) | 0.545 | |||
| Cystatin C, mg/L | 1.2 (1.0, 1.5) | 1.1 (0.9, 1.5) | 0.575 | |||
| CK, U/L | 453.0 (184.0, 1352.0) | 501.0 (172.0, 1406.0) | 0.588 | |||
| CKMB, U/L | 49.0 (24.0, 129.0) | 48.0 (25.0, 126.0) | 0.959 | |||
| LDH, U/L | 360.0 (264.0, 609.0) | 390.0 (270.0, 657.0) | 0.287 | |||
| α-HBDH, U/L | 251.0 (171.0, 459.0) | 281.0 (183.0, 502.0) | 0.325 | |||
| CTnT, ng/L | 956.6 (204.5, 3291.0) | 1014.0 (157.0, 3315.0) | 0.767 | |||
| BNP, pg/mL | 1094.0 (265.6, 4087.0) | 1013.0 (228.7, 4497.0) | 0.718 | |||
| Glucose, mmol/L | 6.7 (5.6, 8.7) | 6.7 (5.6, 9.0) | 0.795 | |||
| Myoglobin, ng/mL | 375.7 (102.2, 961.6) | 295.5 (91.7, 723.5) | 0.08 | |||
| Procedural features | ||||||
| LM, n (%) | 6 (1) | 6 (3) | 0.199 | |||
| LAD, n (%) | 149 (30) | 79 (38) | 0.071 | |||
| LCX, n (%) | 53 (11) | 19 (9) | 0.576 | |||
| RCA, n (%) | 118 (24) | 51 (24) | 1 | |||
| Intrahospital complications | ||||||
| Post-Ventricular fibrillation, n (%) | 44 (9) | 16 (8) | 0.666 | |||
| Post-Cardiogenic shock, n (%) | 51 (10) | 19 (9) | 0.688 | |||
| Introhospital Mortality, n (%) | 69 (14) | 29 (13) | 0.995 | |||
| Other | ||||||
| Total hospital duration stay, d | 7.0 (5.0, 10.0) | 6.0 (5.0, 9.0) | 0.136 | |||
Notes: Values are expressed as medians with interquartile ranges for continuous data. Other values are presented as numbers and percentages.
Abbreviations: Shock index, ratio of HR to SBP; SIRI, systemic inflammatory response index; SII, systemic inflammatory reaction index; PLR, ratio of platelets to lymphocytes; NLR, the ratio of neutrophils to lymphocytes; MLR, ratio of monocytes to lymphocytes; OHCA, out-of-hospital cardiac arrest; GRACE, Global Registry of Acute Coronary Events score; α-HBDH, α-Hydroxybutyrate dehydrogenase; BNP, B-type natriuretic peptides.