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. 2021 Aug 21;16:5675–5692. doi: 10.2147/IJN.S318363

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© 2021 Liu et al.

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Characteristics of R-M@CS-PAA NPs. (A) The morphologies of CS-PAA NPs, R848@CS-PAA NPs, MnCl₂@CS-PAA NPs, and R-M@CS-PAA NPs were observed by TEM. (B and C) Particle sizes (B) and zeta potentials (C) of R-M@CS-PAA NPs in 1640 medium containing 10% FBS at the indicated time points. (D and E) Release profiles of MnCl₂ (D) and R848 (E) from R-M@CS-PAA NPs. *p < 0.05, **p < 0.01.