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. 2021 Aug 25;11:17161. doi: 10.1038/s41598-021-96614-y

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Flowchart showing the inclusion and exclusion criteria of the OSCC patients recruited to engage in this cohort study. A total of 7,763 patients who were diagnosed with oral cancer were recruited in this study. After matching aspirin users with non-users based on 1:4 propensity score analysis, there was a final inclusion of 1,525 OSCC patients were recruited for data analysis in this study. ^aClinical and Pathological AJCC Cancer Staging 7th Edition; ^bClinical AJCC Cancer Staging 7th Edition; ^cPathological AJCC Cancer Staging 7th Edition.