Table 3.
Univariate and multivariate Cox proportional hazards of prognostic factors for OSCC survival, Model B: adjusted for pathological TN staging system and other covariates as shown in the table.
| Variables | Cohort n = 1525 | Hazard ratio (95%CI) | |||
|---|---|---|---|---|---|
| Univariate | p value | Multivariate | p value | ||
| Gender | |||||
| Female | 78(5.11%) | 1 | 0.0843 | 1 | 0.3384 |
| Male | 1447(94.89%) | 1.94(0.91–4.11) | 1.45(0.68–3.10) | ||
| Age | |||||
| Years | 1525(100.00%) | 1.00(0.99–1.01) | 0.7096 | 1.01(1.00–1.02) | 0.0745 |
| Pathological T staginga | |||||
| T1, 2 & 3 | 1219(79.93%) | 1 | < 0.0001 | 1 | 0.0012 |
| T4 | 306(20.07%) | 3.11(2.43–3.98) | 1.57(1.20–2.07) | ||
| Pathological N stagingb | |||||
| N0 | 1140(74.75%) | 1 | < 0.0001 | 1 | < 0.0001 |
| N1, 2 & 3 | 385(25.25%) | 4.25(3.34–5.42) | 2.63(1.99–3.47) | ||
| Treatments | |||||
| Surgery | 857(56.2%) | 1 | < 0.0001 | 1 | < 0.0001 |
| Surgery and RT or CCRT | 668(43.8%) | 4.31(3.27–5.68) | 2.30(1.63–3.25) | ||
| Aspirin use | |||||
| No | 1220(80.0%) | 1 | < 0.0001 | 1 | < 0.0001 |
| Yes | 305(20.0%) | 0.44(0.30–0.64) | 0.44(0.30–0.64) | ||
95% CI 95% Confidence interval, RT Radiotherapy, CCRT Concurrent chemoradiotherapy.
aPathological T Staging 7th Edition.
bPathological N Staging 7th Edition.