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Porcine knees at one year after ACL transection with no further treatment (left panel), ACL reconstruction (center panel) and scaffold-enhanced ACL repair (right panel). In the ACL transection and ACL reconstruction knees, breakdown of the cartilage in the medial femoral condyle is noted (red arrows), while in the scaffold enhanced repair group, there was no significant loss of cartilage integrity (green arrow; adapted from Murray and Fleming, AJSM 201334).
