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. Author manuscript; available in PMC: 2022 Sep 14.
Published in final edited form as: Neurosci Lett. 2021 Jul 17;761:136119. doi: 10.1016/j.neulet.2021.136119

Figure 2:

Figure 2:

Hind limb cast immobilization and chronic alcohol separately and additively produce mechanical hypersensitivity. There was a significant main effect of alcohol (p=0.0072) and a significant main effect of casting (p=0.0232) to decrease paw withdrawal thresholds. There was no significant main effect of ovariectomy (OVX) or significant OVX interactions. Data were analyzed using 3-way ANOVA. Data are represented as mean ± SEM. Control diet + sham surgery, solid navy (n = 5); control diet + OVX, navy dotted (n = 5); alcohol diet + sham surgery, solid orange (n = 5); alcohol diet + OVX, orange dotted (n = 4).