Table 1.

TCR gene usage of CD4 + HLA-DQ8-HIPL11C tetramer⁺ T cells in T1D patients ET600, ET650, and ET672 PBMC.

Clone	TRAV	TRAJ	CDR1α	CDR2α	CDR3α	TRBV	TRBJ	TRBD	CDR1β	CDR2β	CDR3β	No. clone
ET600-1	26-1	33*01	TISGNEY	GLKN	CIVRDSNYQLIW	29-1	1-2*01	1*01	SQVTM	ANQGSEA	CSANRDGGGYTF	7
ET600-2	8-3	22*01	YGATPY	YFSGDTL	CAVGGTSGSARQLTF	10-3	1-2*01	2*01	ENHRY	SYGVKD	CAISEGERGSNYGYTF	6
ET600-3	8-3	27*01	YGATPY	YFSGDTL	CAVGFNAGKSTF	5-1	1-1*01	1*01	SGHRS	YFSETQ	CASSLGPTGTNTEAFF	1
ET600-4	14/DV4	39*01	TSDPSYG	QGSYDQQ	CAMRPNNAGNMLTF	15	1-5*01	1*01	LNHNV	YYDKDF	CATSRGNQGPNQPQHF	1
ET600-5	26-1	39*01	TISGNEY	GLKN	CIVRVNNAGNMLTF	28	1-2*01	2*01	MDHEN	SYDVKM	CASSRLDNGYTF	1
ET600-6	12-2	15*01	DRGSQS	IYSNG	CAVNQAGTALIF	11-1	2-1*01	1*01	SGHAT	FQDESV	CASSWAYNEQFF	1
ET600-7	3	6*01	VSGNPY	YITGDNLV	CAVRDGGSYIPTF	7-8	2-7*01	1*01	SGHVS	FQNEAQ	CASSLLPDRGHEQYF	1
ET600-8	19	9*01	TRDTTYY	RNSFDEQ	CALSEVNTGGFKTIF	10-3	2-6*01	1*01	ENHRY	SYGVKD	CAISLQGSRSGANVLTF	1
ET650-1	26-1	54*01	TISGNEY	GLKN	CIVRVEIQGAQKLVF	5-1	2-5*01	1*01	SGHRS	YFSETQ	CASSLGPGLRETQYF	4
ET650-2	26-1	39*01	TISGNEY	GLKN	CIVRVGYNAGNMLTF	20-1	1-5*01	2*01	DFQETT	SNEGSKA	CSAIAGPNQPQHF	3
ET650-3	26-1	42*01	TISGNEY	GLKN	CIVRPQKGGSQGNLIF	3-1	2-3*01		LGHDT	YNNKEL	CASSHHSTDTQYF	2
ET650-4	26-1	42*01	TISGNEY	GLKN	CIVRVAIEGSQGNLIF	5-1	1-3*01	1*01	SGHRS	YFSETQ	CASSLRRGDTIYF	1
ET650-5	26-1	9*01	TISGNEY	GLKN	CIVRLQSGGFKTIF	20-1	1-2*01	1*01	DFQETT	SNEGSKA	CSAYSPGDRDFSNYGYTF	1
ET650-6	39	54*01	TTSDR	LLSNGAV	CAVDIQGAQKLVF	7-8	2-3*01	1*01	SGHVS	FQNEAQ	CASSLRTAISRTDTQYF	1
ET650-7	30	48*01	KALYS	LLKGGEQ	CGTLAFGNEKLTF	19	1-6*01	2*01	LNHDA	SQIVND	CASHRGKGNSPLHF	1
ET650-8	35	49*01	SIFNT	LYKAGEL	CAGQLWNTGNQFYF	11-1	2-3*01	2*01	SGHAT	FQDESV	SHLRGASTDTQ	1
ET672-1	12-2	48*01	DRGSQS	IYSNGD	CAVNHGNEKLTF	18	1-1*01	1*01	KGHSH	LQKENI	CASSPWEGRMDTEAFF	18
ET672-2	12-1	37*02	NSASQS	VYSSGN	CVVVSNTGKLIF	23-1	2-1*01	2*01	KGHTF	FQNEQV	CASSQWVSGEDEQFF	1