TABLE 2.

Predictive models for identified outcomes with C statistics and probability of true positive and 95% Cis

TM Outcome	No. of Patients	Predictors (+1 point each)	C Statistic (95% CI)	Risk Index Score	Probability of True Positive (95% CI)	No. of True Positives/Total No.
DEFUSE 3
5- to 23-hr time window	145 (all CVA)	NIHSS score <17; CTA ASPECTS 5–7; age <55 yrs	0.71 (0.63–0.79)	0	0.12 (−0.01 to 0.25)	3/25
				1	0.33 (0.22–0.44)	23/70
				2	0.58 (0.42–0.73)	23/40
				3	0.80 (0.55–1.05)	8/10
5- to 15-hr time window	56 (confirmed LVO)	NIHSS score <18; CTA ASPECTS >5; age <65 yrs	0.85 (0.75–0.95)	0	0.08 (−0.07 to 0.24)	1/12
				1	0.32 (0.11–0.53)	6/19
				2	0.80 (0.60–1.00)	12/15
				3	0.90 (0.71–1.09)	9/10
EXTEND
4.5- to 12-hr time window	54 (all CVA)	NIHSS score <18; CTA ASPECTS >5; age <60 yrs	0.86 (0.76–0.97)	0	0.14 (−0.12 to 0.40)	1/7
				1	0.27 (0.01–0.54)	3/11
				2	0.85 (0.69–1.00)	17/20
				3	0.94 (0.82–1.06)	15/16

CVA = cerebrovascular accident.