Table 1.

Simulators for modelling cyber physical systems

Refs.	Simulator	Characteristics	Application in healthcare domain (CPS for coronavirus)
[10]	COSSIM	Open-Source Framework, Ultra-Fast Simulations, simulates software (multicore processors) and hardware components (FPGA devices), Integrate with network and power simulators, more accurate power estimations	The simulation software can model and estimate the power of various medical devices used in coronavirus treatment
[11, 12]	Modelica	Open-source software, Modelica language to model complex CPS and equation modelling for physical elements, real time simulation with event-based triggers, task scheduling based on fixed priority and deadline-based policies, represent network communication with real time issues like noise and delay	It can model the treatment process of patients with identification of equipment need for patients based on their health parameters, Model the clusters of people based on their location tapped through mobile phones for study of transmission rate
[13]	Hybrid	Dymola or MATLAB-Simulink for model and simulation of plant process, Open-source environments like NS-3 or commercial environments like OPNET for simulation of communication network and event-based control in Colored Petri Net	Simulation of communication networks for estimating network reliability and efficient delivery of health status from patients at remote site