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Kaplan-Meier plots for DDR signature cut-off identification. (A) Time-dependent ROC for DDR signature survival prediction in TCGA database; (B) survival difference between high and low DDR signature based on median value; (C) survival difference between high and low DDR signature based on best separation in training cohort; (D) cut-off from TCGA cohort could be useful for risk stratification in ICGC dataset.
