Figure 2.

Sections of human MV with MR display large heterogeneity of thickness, independently of age and gender. (A) Histological sections of human mitral valves representative of three different grades of histological remodeling (patients #7, #4, #11, Supplementary Table 2), stained with Masson trichrome (scale bar represents 1 mm). (B) Thickness of MV leaflet section from male vs. female samples. (C) Correlation between the age of donor and the MV thickness for each donor. Thin dotted line shows the 95% confidence interval. ns, no significant.