Table 2.
Correlation of response rate with biomarkers.
| Response rate | Fisher's exact test | |
|---|---|---|
| N (%) | p-value | |
| PD-L1 | 0.2598 | |
| CPS ≥ 10 (N = 6) | 5 (83.3) | |
| CPS <10 (N = 4) | 2 (50) | |
| Tumor mutation burden* | 0.2703 | |
| TMB ≥ 10 mut/Mb (N = 4) | 3 (75) | |
| TMB <10 mut/Mb (N = 3) | 1 (33) | |
| Platinum sensitivity | 0.4902 | |
| Sensitive (N = 5) | 3 (60) | |
| Refractory (N = 5) | 4 (80) | |
| Tumor site | 0.1753 | |
| Lymph node only (N = 3) | 3 (100) | |
| Other [pelvic, visceral, or mixed] (N = 7) | 4 (57.1) |
Seven of the patients had tumor mutation burden measured.