Fig. 3.

Asthma and the airway microbiome. (a) The volcano plot shows significant differences in the abundance of OTUs between asthmatics and non-smoking subjects with less than 10 packyears of lifetime exposure. Fold change is shown on the x axis and -log10 P (FDR corrected) on the y axis. Relative abundances are reflected in the data point sizes; (b) shows differences in alpha diversity between asthmatics and unaffected non-smoking subjects (boxes show inter-quartile range, notches 95% CI of the median, P values are two-sided from multiple regression).