Table 3.
Clinical studies regarding the use of IABP in cardiogenic shock complicating acute myocardial infarction
| Study | Design | Patients (n) | STEMI | Shock definition | Treatment | Control | Primary endpoint | Result | Follow-up |
|---|---|---|---|---|---|---|---|---|---|
| Ohman et al.31 | RCT | 57 | 100% | Hypotension | TL | No IABP | Total mortality | NS | 6 months |
| Sjauw et al.57 | Meta-Analysis | 1009 | 100% | NA | PCI | No IABP | Total mortality | NS | 30 days |
| Sjauw et al.57 | Meta-Analysis | 10529 | 100% | NA | TL | No IABP | Total mortality | Significant reduction | 30 days |
| Prondzinsky et al.56 | RCT | 40 | 65% | Hypotension | PCI | No IABP | APACHE II score | NS | 4 days |
| Abdel-Wahab et al.60 | Retrospective | 48 | 65% | Hypotension | PCI | IABP post PCI | Total mortality | Significant reduction | In-hospital |
| Romeo et al.63 | Meta-Analysis | 14186 | NA | NA | No reperfusion/TL/PCI | No IABP | Total mortality | NS | In-hospital |
| IABP-SHOCK II16 | RCT | 600 | 69% | Hypotension | PCI/CABG | No IABP | Total mortality | NS | 30 days |
| Unverzagt et al.35 | Meta-Analysis | 790 | NA | NA | PCI/TL/CABG | No IABP/LVAD | Total mortality | NS | 30 days |
| Hawranek et al.41 | Prospective registry | 991 | 81% | Hypotension | Failed PCI | No IABP | Total mortality | Significant reduction | 30 days |
CABG, coronary artery by-pass grafting; IABP, intra-aortic balloon pump; LVAD, left ventricular assist devices; NA, not available; NS, non-significant; PCI, percutaneous coronary intervention; RCT, randomized control trial; STEMI, ST elevation myocardial infarction; TL, thrombolysis.