TABLE 1.
Piglet characteristics and blood gas parameters across age groups taken during MRI (mean ± standard deviation)
| Age relative to term (days) | ||||
|---|---|---|---|---|
| Characteristics | T−9 | T−3 | T+1 | T+5 |
| Sample (male:female) | 5:7 | 6:4 | 5:3 | 1:3 |
| Cord cut to start of 4D flow scan (min) | 49.1 ± 39.1 | 38.2 ± 14.7 | — | — |
| Weight (kg) | 1.07 ± 0.14abc | 1.59 ± 0.23 | 1.47 ± 0.47f | 1.95 ± 0.16 |
| Body temp during 4D flow (ºC) | 34.0 ± 1.5b | 35.0 ± 1.5 | 37.0 ± 0.4f | 33.5 ± 2.4 |
| Cardiovascular data | ||||
| Heart rate—4D flow (bpm) | 153.8 ± 22.0 | 129.1 ± 19.7e | 134.5 ± 20.3f | 179.1 ± 32.2 |
| Heart rate—catheter (bpm) | 156.7 ± 24.8 | 132.1 ± 23.4e | 145.4 ± 33.1 | 192.9 ± 45.5 |
| Mean arterial pressure (mmHg) | 47.1 ± 6.6c | 53.3 ± 8.1 | 49.4 ± 13.6f | 68.8 ± 17.1 |
| Systolic blood pressure (mmHg) | 55.2 ± 5.5c | 62.5 ± 11.3e | 63.6 ± 15.6f | 94.1 ± 21.6 |
| Diastolic blood pressure (mmHg) | 43.1 ± 7.9 | 47.2 ± 7.6 | 42.4 ± 12.7 | 56.1 ± 15.3 |
| Blood gas parameters | ||||
| PaO2 (mmHg) | 223.8 ± 165.2 | 195.6 ± 97.2 | 276.3 ± 157.8 | 280.8 ± 38.7 |
| PaCO2 (mmHg) | 42.5 ± 19.0 | 53.9 ± 33.5 | 52.4 ± 27.2 | 32.2 ± 4.9 |
| pH | 7.451 ± 0.216 | 7.417 ± 0.250 | 7.358 ± 0.224 | 7.444 ± 0.078 |
| SaO2 (%) | 93.2 ± 7.4 | 95.0 ± 3.8 | 93.0 ± 6.8 | 93.0 ± 8.6 |
| Hematocrit (%) | 26.9 ± 3.0 | 24.2 ± 4.2 | 25.8 ± 2.2 | 21.3 ± 4.9 |
| Hemoglobin (g/L) | 91.6 ± 9.9 | 82.0 ± 14.6 | 87.5 ± 8.3 | 71.8 ± 16.5 |
| Lactate (mmol/L) | 4.13 ± 1.68bc | 4.49 ± 1.67de | 1.75 ± 0.98 | 0.78 ± 0.27 |
| Glucose (mmol/L) | 4.45 ± 1.87 | 3.98 ± 1.90 | 6.02 ± 1.29 | 5.90 ± 1.49 |
Parameter differences across age groups were tested using one‐way ANOVA. Inter‐group significant differences are labeled: a: T‐9 versus T‐3; b: T‐9 versus T+1; c: T‐9 versus T+5; d: T‐3 versus T+1; e: T‐3 versus T+5; f: T+1 versus T+5.