Table 2.
Genotype and allele frequencies of the 6 SYTL3- SLCC2A3 SNPs in cases and controls [n(%)].
| Genotype | Control (n 755) | CAD (n = 758) | IS (n = 756) | Allele | Control (n = 1,510) | CAD (n = 1,516) | IS (n = 1,512) |
|---|---|---|---|---|---|---|---|
| rs9364496 | |||||||
| AA | 481 (63.7) | 448 (59.1) | 486 (64.3) | ||||
| AG | 237 (31.4) | 276 (36.4) | 234 (30.9) | A | 1199 (79.4) | 1172 (77.3) | 1206 (79.8) |
| GG | 37 (4.9) | 34 (4.5) | 36 (4.8) | G | 311 (21.6) | 344 (23.7) | 306 (20.2) |
| x 2 | 4.258 | 0.058 | 1.958 | 0.060 | |||
| P | 0.119 | 0.971 | 0.162 | 0.807 | |||
| P HWE | 0.268 | 0.298 | 0.257 | ||||
| rs6455600 | |||||||
| CC | 365 (48.3) | 364 (48.0) | 356 (47.1) | ||||
| CT | 332 (44.0) | 332 (43.8) | 327 (43.2) | C | 1062 (70.3) | 1060 (69.9) | 1039 (68.7) |
| TT | 58 (7.7) | 62 (8.2) | 73 (9.7) | T | 448 (29.7) | 456 (30.1) | 473 (31.3) |
| x 2 | 0.129 | 1.867 | 0.061 | 0.929 | |||
| P | 0.938 | 0.393 | 0.805 | 0.335 | |||
| P HWE | 0.140 | 0.256 | 0.868 | ||||
| rs2129209 | |||||||
| AA | 375 (49.7) | 427 (56.3) | 423 (56.0) | ||||
| AC | 328 (43.4) | 282 (37.2) | 294 (38.9) | A | 1078 (71.4) | 1136 (74.9) | 1140 (75.4) |
| CC | 52 (6.9) | 49 (6.5) | 39 (5.2) | C | 432 (28.6) | 380 (25.1) | 372 (24.6) |
| x 2 | 6.924 | 6.602 | 4.838 | 21.577 | |||
| P | 0.031 | 0.037 | 0.028 | 0.001 | |||
| P HWE | 0.081 | 0.791 | 0.185 | ||||
| rs9456350 | |||||||
| AA | 572 (75.8) | 595 (78.5) | 568 (75.1) | ||||
| AG | 173 (22.9) | 153 (20.2) | 178 (23.5) | A | 1317 (87.2) | 1343 (88.6) | 1314 (86.9) |
| GG | 10 (1.3) | 10 (1.3) | 10 (1.3) | G | 193 (12.8) | 173 (10.4) | 198 (12.1) |
| x 2 | 1.674 | 0.085 | 1.335 | 0.066 | |||
| P | 0.433 | 0.959 | 0.248 | 0.797 | |||
| P HWE | 0.446 | 0.963 | 0.343 | ||||
| rs446809 | |||||||
| CC | 378 (50.1) | 370 (48.8) | 360 (47.6) | ||||
| CA | 315 (41.7) | 318 (42.0) | 331 (43.8) | C | 1071 (70.9) | 1058 (69.8) | 1051 (69.5) |
| AA | 62 (8.2) | 70 (9.2) | 65 (8.6) | A | 439 (28.1) | 458 (29.2) | 461 (30.5) |
| x 2 | 0.579 | 0.906 | 1.728 | 1.454 | |||
| P | 0.749 | 0.636 | 0.189 | 0.228 | |||
| P HWE | 0.749 | 0.888 | 0.365 | ||||
| rs539298 | |||||||
| AA | 383 (50.7) | 439 (57.9) | 452 (59.8) | ||||
| AG | 317 (42.0) | 279 (36.8) | 265 (35.0) | A | 1083 (71.7) | 1157 (76.3) | 1169 (77.3) |
| GG | 55 (7.3) | 40 (5.3) | 39 (5.2) | G | 427 (28.3) | 359 (23.7) | 343 (22.7) |
| x 2 | 8.600 | 13.242 | 8.316 | 12.447 | |||
| P | 0.014 | 0.001 | 0.004 | 0.000 | |||
| P HWE | 0.335 | 0.614 | 0.984 | ||||
CAD, coronary artery disease; IS, ischemic stroke.