Table 5.

The P-values for the interactions of genotypes and gender, age, drinking, smoking, and BMI on serum lipid levels and the risk of CAD and IS.

SNP/factor	Lipid							CAD	IS
	TC	TG	HDL-C	LDL-C	ApoA1	ApoB	ApoA1/ApoB
rs9364496
Gender	0.622	0.028	0.004	0.022	0.022	0.003	0.031	0.052	0.089
Age	0.793	0.153	0.645	0.478	0.478	0.275	0.444	0.550	0.430
Smoking	0.004	0.000	0.003	0.002	0.002	0.877	0.136	0.174	0.156
Drinking	0.399	0.020	0.956	0.040	0.023	0.278	0.401	0.022	0.017
BMI	0.000	0.003	0.092	0.006	0.006	0.610	0.083	0.019	0.005
rs6455600
Gender	0.655	0.004	0.004	0.022	0.002	0.071	0.388	0.286	0.366
Age	0.684	0.056	0.828	0.681	0.228	0.992	0.374	0.216	0.164
Smoking	0.473	0.000	0.089	0.002	0.424	0.293	0.013	0.251	0.363
Drinking	0.359	0.030	0.042	0.003	0.056	0.906	0.374	0.221	0.265
BMI	0.006	0.001	0.304	0.010	0.144	0.101	0.004	0.010	0.131
rs2129209
Gender	0.364	0.063	0.012	0.008	0.235	0.021	0.659	0.605	0.005
Age	0.900	0.428	0.688	0.497	0.198	0.479	0.266	0.004	0.407
Smoking	0.849	0.005	0.105	0.011	0.798	0.296	0.061	0.880	0.654
Drinking	0.373	0.002	0.000	0.023	0.102	0.500	0.115	0.020	0.189
BMI	0.001	0.013	0.207	0.006	0.235	0.082	0.006	0.016	0.031
rs9456350
Gender	0.281	0.098	0.021	0.017	0.013	0.026	0.285	0.809	0.162
Age	0.916	0.561	0.084	0.637	0.083	0.679	0.230	0.039	0.281
Smoking	0.933	0.027	0.010	0.023	0.126	0.293	0.027	0.494	0.037
Drinking	0.108	0.010	0.000	0.020	0.017	0.412	0.047	0.008	0.030
BMI	0.011	0.001	0.032	0.006	0.106	0.072	0.005	0.130	0.071
rs446809
Gender	0.314	0.090	0.009	0.005	0.004	0.011	0.013	0.890	0.759
Age	0.215	0.266	0.286	0.009	0.170	0.191	0.009	0.768	0.298
Smoking	0.294	0.032	0.054	0.007	0.463	0.018	0.024	0.281	0.381
Drinking	0.057	0.040	0.001	0.012	0.183	0.049	0.003	0.113	0.167
BMI	0.004	0.013	0.112	0.021	0.225	0.010	0.004	0.005	0.076
rs539298
Gender	0.678	0.002	0.004	0.032	0.002	0.075	0.630	0.781	0.738
Age	0.385	0.131	0.052	0.839	0.033	0.928	0.343	0.006	0.180
Smoking	0.066	0.689	0.030	0.011	0.193	0.374	0.089	0.216	0.143
Drinking	0.097	0.447	0.000	0.003	0.000	0.890	0.103	0.000	0.000
BMI	0.000	0.002	0.045	0.010	0.058	0.003	0.007	0.334	0.200

SNP, single nucleotide polymorphism; TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; ApoA1, apolipoprotein A1; ApoB, apolipoprotein B; CAD, coronary artery disease; IS, ischemic stroke; BMI, body mass index. P ≤ 0.00125 was considered statistically significant after Bonferroni correction.