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NEUROG3 binds to transcription factor genes enriched in islet cell types. (A) Enriched expression of transcriptional regulators in islet cell types, NKX6-1 for beta cells and IRX1, IRX2 for alpha cells, in the human fetal pancreas (taken from https://descartes.brotmanbaty.org). Expression of INS and GCG is provided to define developing beta and alpha cells, respectively. (B–C) NEUROG3 binding to NKX6-1 (B) and IRX1-IRX2 (C) loci. See Figure 2E for legend description.
