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. Author manuscript; available in PMC: 2021 Aug 26.
Published in final edited form as: J Neurotrauma. 2017 Jun 5;34(21):2972–2981. doi: 10.1089/neu.2016.4814

Table 1.

Serum Testosterone Concentrations and Circulating Bone Turnover Markers after Sham Surgery (T9 Laminectomy) or Severe Spinal Cord Injury (SCI) Alone or in Combination with Testosterone-Enanthate (TE) or TE Plus Finasteride (TE+FIN)

SHAM (a) SCI (b) SCI+TE (c) SCI+TE+FIN (d)
Testosterone (week 4), ng/mL 3.7 ± 0.8c*,d* 1.9 ± 0.5c*,d* 6.8 ± 0.5a*,b*,d* 10.0 ± 0.9a*,b*,c*
Testosterone (week 8), ng/mL 3.3 ± 0.7c*,d* 1.5 ± 0.3c*,d* 7.8 ± 1.5a*,b* 10.9 ± 1.6a*,b*
Trap5b, U/L 3.4 ± 0.2c*,d 2.9 ± 0.1 2.4 ± 0.2a*   2.8 ± 0.3a
P1NP, ng/mL  26 ± 3  34 ± 4c*,d  21 ± 2b*    24 ± 2b

Values are means ± standard error; n = 7–12/group.

Letters a–d indicate differences from respectively labeled groups at p < 0.05 or *p < 0.01 (a = vs. SHAM, b = vs. SCI, c = vs. SCI+TE, and d = vs. SCI+TE+FIN). Trap5b is a circulating marker of bone resorption. P1NP is a circulating marker of bone formation.

Trap5b, tartrate resistant acid phosphatase 5b; P1NP, procollagen type 1 N-terminal propeptide.