Figure 3.

(a) Liver cell necrosis was quantified in the sham, CCl₄, MSC-CM, and MSC-CM + SMGO groups. Treatment with SMGO reduced infiltration of neutrophils and activation of Kupffer cells; (b) Kupffer cell activation was assessed by labeling CD68 in sections 96 h after operation; and (c) neutrophil infiltration was visualized by MPO immunostaining in sections 96 h after operation. *P < 0.05, **P < 0.01; ##P < 0.01. Abbreviations: CM, conditioned medium; CCl₄, carbon tetrachloride; and SMGO, silica magnetic graphene oxide.