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. 2021 Aug 10;6(33):21194–21206. doi: 10.1021/acsomega.0c05395

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© 2021 The Authors. Published by American Chemical Society

Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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Effects of SMGO on the expression of VEGF and MMP-9 in the damaged livers treated with MSC-CM. MGO enhanced the number of VEGF and MMP-9-positive cells in the CCl₄-induced livers treated with MSC-CM. Positive cells were visualized by VEGF and MMP-9 immunostaining in the liver sections 4 days after the injection. Scale bar, 200 μm (control, CCl₄ + SMGO, and CCl₄ + CM + SMGO); Scale bar, 400 μm (CCl₄, CCl₄ + CM). Arrows mark MMP9+ and VEGF + cells. Scale bars, 200 μm (A,B,E,F,K,L) and 400 μm (C,D,G,H). Abbreviations: CM, conditioned medium; CCl₄, carbon tetrachloride; and SMGO, silica magnetic graphene oxide.