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Treatment with MSC-CM + SMGO after 3 days decreased the levels of proinflammatory cytokines IL-6 and Caspase-3 in liver failure induced by CCl4 compared to treatment with either SMGO or MSC-CM. Sections stained with H&E, IL-6, and Caspase-3. Abbreviations: CM, conditioned medium; CCl4, carbon tetrachloride; and SMGO, silica magnetic graphene oxide. Arrows mark inflammatory (H&E), Casp3+, and IL6+ cells. Scale bars, 200 μm (A–C,H,G,N–P) and 400 μm (D–F,K–M).
