Table 3. Microscopic Evaluation of Hepatocytes in Different Treatment Groupsa.
| sample | average apoptotic cells per field | % apoptosis | accumulation of inflammatory cells | hyperemia |
|---|---|---|---|---|
| control | – | 0 | – | – |
| sham | – | 0 | – | – |
| CCl4 | 62 | 17.71 | +++ | +++ |
| SMGO | 20 | 5.70 | ++ | ++ |
| MSC-CM | 33 | 9.42 | + | + |
| MSC-CM + SMGO | 6 | 1.71 | ++ | ++ |
a
Treatment with SMGO improved the effects of MSC-CM on histopathologic appearance. −, +, ++, and +++ were used to assess hyperemia and accumulation of inflammatory cells and indicate no effect, slight, mild, and intensive, respectively.