TABLE 4.
Mean life span of control strains lacking FLP
Genotype | Life span (mean ± SEM) (days) of:
|
% Change (HP − Co)/Coa | P (HP versus Co) | |
---|---|---|---|---|
Co | HP | |||
Expt 1 | ||||
SOD3A1 | 38.71 ± 0.68 | 31.97 ± 0.79 | −17.40* | <0.0001 |
SOD3B2 | 39.40 ± 0.77 | 37.03 ± 0.76 | −6.01* | 0.0278 |
SOD2A;SOD3A1 | 65.09 ± 1.13 | 68.89 ± 0.77 | +5.84 | 0.0540 |
CAT2A2 | 35.26 ± 0.87 | 31.11 ± 0.66 | −11.77* | <0.0001 |
CAT2B12 | 39.21 ± 1.10 | 35.40 ± 1.02 | −9.73* | 0.0108 |
CAT2A2;SOD3A1 | 40.96 ± 0.87 | 38.90 ± 0.73 | −5.03 | 0.0704 |
CAT2A2;SOD3B2 | 31.97 ± 0.71 | 31.62 ± 0.65 | −1.11 | 0.7338 |
CAT2B12;SOD3B2 | 46.37 ± 0.97 | 43.69 ± 0.79 | −5.77* | 0.0332 |
LacZ | 34.73 ± 1.41 | 31.20 ± 1.33 | −10.17 | 0.0672 |
Expt 2 | ||||
SOD3A1 | 38.42 ± 0.73 | 33.34 ± 0.51 | −13.22* | <0.0001 |
SOD3B2 | 42.56 ± 0.89 | 41.22 ± 0.97 | −3.15 | 0.3078 |
SOD2A;SOD3A1 | 56.39 ± 1.06 | 54.69 ± 0.98 | −3.02 | 0.2802 |
CAT2A2 | 38.01 ± 0.87 | 35.57 ± 0.57 | −6.42* | 0.0192 |
CAT2B12 | 40.81 ± 1.13 | 36.84 ± 1.31 | −9.72* | 0.0214 |
CAT2A2;SOD3A1 | 46.10 ± 0.63 | 39.42 ± 0.65 | −14.51* | <0.0001 |
CAT2A2;SOD3B2 | 41.38 ± 0.77 | 37.01 ± 0.57 | −10.54* | <0.0001 |
CAT2B12;SOD3B2 | 52.76 ± 1.46 | 51.77 ± 1.17 | −1.88 | 0.5962 |
LacZ | 32.76 ± 1.64 | 31.70 ± 1.45 | −3.22 | 0.6312 |
∗, statistically significant change.