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. 2021 Mar 1;37(16):2259–2265. doi: 10.1093/bioinformatics/btab125

Table 2.

Performance of selecting causal omics variables under different B shapes for different methods, including tensor regression evaluated at true rank (TR.true), at AIC determined rank (TR.AIC) and at BIC determined rank (TR.BIC), as well as linear regression model (LM) and LASSO on vectorized omics variables, based on 200 replications

B shape = Flat
B shape = I
B shape = T
B shape = Random
TR. TR. TR. LM LASSO TR. TR. TR. LM LASSO TR. TR. TR. LM LASSO TR. TR. TR. LM LASSO
true AIC BIC true AIC BIC true AIC BIC true AIC BIC
d= 0.125
TPR 0.371 0.370 0.371 0.274 0.683 0.695 0.698 0.695 0.214 0.664 0.736 0.744 0.981 0.669 0.832 0.626 0.849 0.892 0.396 0.796
FDR 0.044 0.047 0.044 0.257 0.275 0.222 0.146 0.222 0.331 0.429 0.127 0.094 0.442 0.076 0.317 0.043 0.032 0.027 0.053 0.184
F-measure 0.530 0.529 0.530 0.398 0.702 0.731 0.756 0.731 0.321 0.613 0.797 0.813 0.711 0.776 0.750 0.756 0.899 0.929 0.557 0.806
d= 0.25
TPR 0.649 0.649 0.649 0.564 0.753 0.795 0.870 0.873 0.554 0.855 0.868 0.899 0.973 0.809 0.939 0.860 0.872 0.969 0.709 0.914
FDR 0.033 0.033 0.033 0.141 0.320 0.235 0.118 0.116 0.158 0.423 0.141 0.057 0.288 0.061 0.332 0.032 0.034 0.044 0.030 0.189
F-measure 0.773 0.773 0.773 0.679 0.714 0.779 0.875 0.877 0.666 0.688 0.863 0.919 0.807 0.869 0.780 0.911 0.915 0.962 0.819 0.860
d= 1
TPR 0.954 0.954 0.954 0.932 0.965 0.815 0.914 0.914 0.895 0.957 0.967 0.979 0.980 0.971 0.990 0.961 0.960 0.961 0.936 0.967
FDR 0.036 0.037 0.036 0.093 0.412 0.238 0.107 0.106 0.103 0.475 0.081 0.055 0.053 0.055 0.350 0.025 0.026 0.025 0.025 0.231
F-measure 0.954 0.954 0.954 0.919 0.730 0.785 0.902 0.903 0.895 0.677 0.942 0.962 0.963 0.957 0.784 0.968 0.967 0.968 0.955 0.856

Note: TPR = true positive rate; FDR = false discovery rate; d indicates the effect strength of causal omics variables. For TR and LM, a variable is selected as important if P-value < 0.05. The best performed methods among TR.AIC, LM and LASSO, judged by F-measures, are shown in shaded cells.