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. 2020 Nov;20(10):729–740. doi: 10.2174/1568009620666200619123725

Table 1.

Role of alternative splicing (AS) in human tumor immunity.

graphic file with name CCDT-20-729_T1.jpg

✓represents splice pattern corresponding to splice isoform on left column. ‘New’ aindicates new insert sequence.

RI: intron retention; SE: exon skipping; ATF: activating transcription factor; MLL5: mixed-lineage leukemia-5; spe: special; NK cell: natural killer cell; MHC: major histocompatibility complex; CD200S: truncated forms of CD200; CD200L: full-length CD200; TIGIT: T cell Ig and ITIM domain; PVR: poliovirus receptor; IFN γ: interferon γ; CTLs: cytotoxic T lymphocytes. DLBCL: diffuse large B cell lymphoma; U2AF1: U2 small nuclear RNA auxiliary factor 1; IRAK4-L: long isoform of interleukin-1 receptor-associated kinase 4; CRC: colorectal cancer; NSCLC: non-small cell lung cancer; HCC cell: hepatocellular carcinoma.