TABLE 3.
Mapping of KSR1 sites phosphorylated by MAPK in vitro
| HPLC fraction(s) | Edman degradationb | Phosphoamino acid(s) | Amino acid residues spanned by deletion mutant | Site identified (sequencea) |
|---|---|---|---|---|
| 37–38 | 6 | T | 249–320 | T274 (LKPPRT*PPPPSR) |
| 53 | 11 | T | 249–320 | T260 (ALHSFITPPTT*PQLR) |
| 59 | S, T | 424–539 | S443? | |
| 61–62 | S, T | 424–539 | S443? | |
| 65–66 | S, T | 249–320 | ? |
Asterisks indicate sites of phosphorylation.
Cycle in which 32P counts per minute were released.