Table 4.
Comparison between baseline angiotensin receptor neprilysin inhibitor 0 and angiotensin receptor neprilysin inhibitor 6 after 6 months follow up
| Groups | n | Mean±SD | t | P |
|---|---|---|---|---|
| LVEDV (mL) | ||||
| AR 0 | 34 | 155.35±29.67 | 0.429 | 0.669 |
| AR 6 | 34 | 152.24±30.21 | ||
| LVESV (mL) | ||||
| AR 0 | 34 | 102.23±19.03 | 0.627 | 0.533 |
| AR 6 | 34 | 99.06±22.59 | ||
| EF (%) | ||||
| AR 0 | 34 | 34.77±3.62 | −1.124 | 0.265 |
| AR 6 | 34 | 35.77±3.72 | ||
| Average LVGLS (%) | ||||
| AR 0 | 34 | −9.77±1.83 | 0.811 | 0.420 |
| AR 6 | 34 | −10.12±1.77 | ||
| TR velocity (m/s) | ||||
| AR 0 | 34 | 2.73±0.30 | 2.271 | 0.026 |
| AR 6 | 34 | 2.57±0.31 | ||
| TR grade | ||||
| AR 0 | 34 | 2.50±0.93 | 1.848 | 0.069 |
| AR 6 | 34 | 2.12±0.77 | ||
| MR grade | ||||
| AR 0 | 34 | 2.71±0.84 | 2.951 | 0.004 |
| AR 6 | 34 | 2.12±0.81 | ||
| E/A | ||||
| AR 0 | 34 | 1.14±0.31 | 2.675 | 0.009 |
| AR 6 | 34 | 0.95±0.30 | ||
| E/e’ | ||||
| AR 0 | 34 | 10.62±1.88 | 3.135 | 0.003 |
| AR 6 | 34 | 9.21±1.84 | ||
| DD grade | ||||
| AR 0 | 34 | 2.18±0.52 | 2.651 | 0.010 |
| AR 6 | 34 | 1.82±0.58 | ||
| Untwist rate (°/s) | ||||
| AR 0 | 34 | −61.21±4.73 | 3.142 | 0.003 |
| AR 6 | 34 | −65.00±5.22 | ||
| Untwist onset (ms) | ||||
| AR 0 | 34 | 104.53±16.81 | 1.498 | 0.139 |
| AR 6 | 34 | 98.41±16.87 | ||
| Twist | ||||
| AR 0 | 34 | 8.88±1.49 | −0.313 | 0.755 |
| AR 6 | 34 | 8.98±1.31 | ||
| Basal rotation | ||||
| AR 0 | 34 | −3.56±0.86 | −0.123 | 0.902 |
| AR 6 | 34 | −3.56±0.85 | ||
| Apical rotation | ||||
| AR 0 | 34 | 4.52±1.39 | 0.117 | 0.907 |
| AR 6 | 34 | 4.48±1.29 |
AR 0 baseline, AR 6 6 months follow up. AR=ARNI group, ARNI=Angiotensin receptor neprilysin inhibitor, SD=Standard deviation, LV=Left ventricular, LVEDV=LV end-diastolic volume, LVESV=LV end-systolic volume, EF=Ejection fraction, LVGLS=LV global longitudinal strain, TR=Tricuspid regurgitation, DD=Diastolic dysfunction, MR=Mitral regurgitation