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. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: Free Radic Biol Med. 2021 May 11;171:99–111. doi: 10.1016/j.freeradbiomed.2021.05.012

Fig. 3. Endogenous KISS1 knockdown exacerbated short-term outcomes at 24 h after SAH.

Fig. 3

(A) Representative western blot bands of KISS1, 4HNE, HO1，Bcl2, and BAX; (B) Densitometric quantification of KISS1, 4HNE, HO1, Bcl2, and BAX at 24 h after SAH; (C) KISS1 siRNA knockdown significantly aggravated the neurological deficits, resulting in the lower modified Garcia score and beam balance score in SAH rats than SAH alone or scramble siRNA-treated SAH; (D, E) Representative western blot bands and densitometric quantification of KISS1 demonstrated the knockdown efficacy of KISS1 siRNA on brain KISS protein levels in naïve and SAH rats, *P < 0.05, **P < 0.01. Data was represented as mean ± SD. n = 4–10/group. One-way ANOVA, Tukey’s post hoc test.