Table 1.

GRADE Summary of Findings for Meta-Analyses on Molar Mesial Movement During Incisor Retraction^a

Quality Assessment, Outcome: Mean Difference of Molar Mesial Movement During Anterior Retraction
Question: Will the Use of TPA Anchorage Have an Effect on the Mesial Molar Movement During Anterior Teeth Retraction?
No. of Studies According to Meta-Analyses Anchorage Groups	Study Design	Risk of Bias	Inconsistency	Indirectness	Imprecision	Other Considerations
7 (Figure 2)	Randomized trials	Seriousb,c	Not serious	Not serious	Not serious	Strong association
4 (Figure 3)	Observational studies	Seriousb	Not serious	Not serious	Not serious	Strong association
3 (Figure 4)	Observational studies	Seriousb,c	Not serious	Not serious	Not serious	Publication bias strongly suspected

^aCI indicates confidence interval; RR, risk ratio.

^bInconsistent study design.

^cMany of these studies did not consider blinding of the participants and outcome assessors.