Representative image of genotyped variants on interleukin 1 and osteopontin cluster genes mapped to human chromosomes 2 and 4, where the polymorphisms are represented. The IL1B, IL1RN, and SPP1 genes contain different polymorphisms, although the schema represents only the SNPs studied in this research (rs1143634, rs419598, rs9138, and rs11730582). Vertical bars represent the part of the gene that encodes the proteins.