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. 2021 Jul 22;10(8):890. doi: 10.3390/antibiotics10080890

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Sections were taken from a skin wound on day 7. (a) An untreated wound demonstrated epidermal loss (arrow), as well as dermal and epidermal separation (star). Inflammatory cells (arrowhead) are apparent, as are several fibroblast cells (circle), as well as congested blood vessels (BV) and regular collagen fibers (C). (b) A wound treated with DEEL showed epidermal loss (arrow), epidermal layer regeneration (E) with inflammatory cells (arrowhead), collagen fibers (C), and several fibroblast cells (circle). (c) An MRSA-infected wound displayed extensive inflammatory cells (arrowhead) as well as necrotic tissue (star). (d) MRSA-infected wound + DEEL treatment showed wound re-epithelialization (E) with significant inflammatory cells (arrowhead), aggregation, and fibroblast proliferation (circle) (H&E X200).