Table 1.
The physicochemical properties of Brevinin-2GUb and its analogues.
| Peptide | Sequence | Hydrophobicity <H> | Hydrophobic Moment <μH> | Net Charge (z) |
|---|---|---|---|---|
| Brevinin-2GUb | GVIIDTLKGAAKTVAAELLRKAHCKLTNSC | 0.379 | 0.144 | +3 |
| tB2U | GVIIDTLKGAAKTVAAELLRKAH-NH2 | 0.346 | 0.288 | +2 |
| tB2U-α | GVIIDTLKGAAKTVAAELL-NH2 | 0.501 | 0.339 | 0 |
| tB2U-K | GVIIKTLKGAAKTVAAKLL-NH2 | 0.471 | 0.347 | +4 |
| 7-tB2U-K 1 | GVIIKTL-NH2 | - | - | +1 |
| 14-tB2U-K | GVIIKTLKGAAKTV-NH2 | 0.422 | 0.506 | +3 |
| tB2U-6K | GVIIKKLKGAAKKVAAKLL-NH2 | 0.339 | 0.410 | +6 |
1 The hydrophobicity and hydrophobic moment of 7-tB2U-K cannot be analysed by Heliquest due to the short length of the sequence.