Table 5.
The MBICs and minimum biofilm eradication concentrations (MBECs) of Brevinin-2GUb and its derivatives 1.
| Bacteria Strains | MBIC/MBEC (μM) | ||||||
|---|---|---|---|---|---|---|---|
| Brevinin-2GUb | tB2U | tB2U-α | tB2U-K | tB2U-6K | 7-tB2U-K | 14-tB2U-K | |
| S. aureus | 256/>512 | >512 | >512 | 16/>512 | 64/>512 | 512/>512 | >512 |
| E. coli | 128/>512 | >512 | >512 | 16/>512 | 2/>512 | >512 | >512 |
| K. pneumoniae | >512 | >512 | >512 | 128/>512 | 32/>512 | >512 | >512 |
| P. aeruginosa | >512 | >512 | >512 | 128/>512 | 32/>512 | >512 | >512 |
| MRSA | 256/>512 | 128/>512 | >512 | 16/>512 | 32/>512 | 512/>512 | >512 |
| E. faecalis | >512 | 256/>512 | >512 | 32/>512 | 64/>512 | >512 | >512 |
1 The results were achieved from the fifteen replicates in three independent tests.