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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: Clin Pharmacol Ther. 2020 Oct 25;109(3):728–738. doi: 10.1002/cpt.2041

Table 1.

Participant characteristics.

Oral (N=32) Transdermal (N=28)
Age (years)1 50 ± 14 48 ± 9.9
Menopause
 Pre 18 (56%) 18 (64%)
 Post 14 (44%) 10 (36%)
Race
 European 25 (78%) 24 (86%)
 Non- European 7 (22%) 4 (14%)
Indication for mastectomy
 Invasive cancer 13 (41%) 17 (61%)
 DCIS 8 (25%) 2 (7%)
 Non-cancer 11 (34%) 9 (32%)
Mastectomy with Tumescence 18 (56%) 19 (68%)
Breast size (cup size)
 Small (A&B) 15 (47%) 11 (39%)
 Medium/Large (≥C) 15 (47%) 16 (57%)
 Not available 2 (4%) 1 (4%)
BMI
 Normal (<25) 17 (53%) 10 (36%)
 Overweight (25–29.9) 6 (19%) 10 (36%)
 Obese (≥30) 8 (25%) 8 (29%)
 Not available 1 (3%) 0 (0%)
Tumor markers, clinical assays (N=21) (N=19)
ER status
 Positive 18 (86%) 15 (79%)
 Negative (<1%) 3 (14%) 2 (16%)
 Not available 0 (0%) 2 (11%)
PR status
 Positive 15 (71%) 14 (73%)
 Negative (<1%) 5 (24%) 3 (11%)
 Not available 1 (5%) 2 (11%)
HER-2 status
 Positive 0 (0%) 2 (10.5%)
 Negative 13 (62%) 15 (79 %)
 Not available2 8 (38%) 2 (10.5%)
Tumor size (cm)1 1.5 ± 1.1 2.2 ± 1.7
1

Age and tumor size are reported as mean ± SD. Tumor size was not available for one subject in transdermal group (N=18).

2

HER-2 status was not available for DCIS cases.