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. 2021 Jul 27;10(8):1202. doi: 10.3390/antiox10081202

Figure 1.

Figure 1

Effects of twenty different amidated amino acids on tyrosinase (TYR)-mediated dopachrome formation in vitro, and the eumelanin content and viability of MNT-1 cells. In (a), TYR-mediated dopachrome formation was determined using a lysate of human embryonic kidney 293 cells constitutively expressing human TYR in the absence (the control) or presence of each substance at 0.2 mM. Data are presented as % of control (means ± SD, n = 4). ** p < 0.01 vs. control. In (b) and (c), MNT-1 cells were treated with vehicle (control) or each substance at 0.5 mM for 72 h. Melanin content (b) and cell viability (c) are presented as % of control (means ± SD, n = 4). ** p < 0.01 vs. control.