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. 2021 Jul 21;10(8):1157. doi: 10.3390/antiox10081157

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The level of pro-inflammatory eicosanoids (prostaglandin E2 (PGE2), leukotriene B4 (LTB4)) (A) and anti-inflammatory eicosanoids (15-deoxy-delta12,14-prostaglandin J2 (15d-PGJ2), 15-hydroxyeicosatetraenoic acid (15-HETE)) (B) in the liver of nude rats in the following groups: treated with CBD (every 12 h) for 4 weeks; irradiated with UVA (every 48 h) and treated with CBD (every 12 h) for 4 weeks; irradiated with UVB (every 48 h) and treated with CBD (every 12 h) for 4 weeks. The mean values for six rats in each group ± SD are shown: x—differences vs. control group, p < 0.05; a—differences vs. UVA treated group, p < 0.05; b—differences vs. UVB treated group, p < 0.05.