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. 2021 Jul 29;10(8):1221. doi: 10.3390/antiox10081221

Table 1.

Baseline demographic and clinical characteristics and final outcomes of the patients who developed acute respiratory distress syndrome, or pneumonia without this criterion.

Characteristics ARDS Non-ARDS p Value
Patients n 29 31
Age, years 67 ± 13 64 ± 9 NS
Male 23 (79.3) 15 (48.4) 0.01
Female 6(20.7) 16 (51.6) 0.01
Smoking status
Active or former smokers 15 (51.7) 7 (11.6) 0.019
Comorbidities
Arterial hypertension 16 (55.2) 15 (48.4) NS
Diabetes mellitus 11 (37.9) 10 (32.3) NS
Dyslipidaemia 12 (41.4) 12 (38.7) NS
Heart disease 4 (13.8) 2 (6.4) NS
Pulmonary disease 3 (10.3) 4 (12.9) NS
Previous treatment
ACE blocker drugs 14 (48.3) 13 (31.9) NS
Inhaled corticoids 1 (3.4) 4 (12.9) NS
SOFA score 3.7 ± 2.5 1.1 ± 1.2 0.000
Respiratory support
Invasive mechanical ventilation 23 (79.3) 0 (0.0) 0.000
High Flow Nasal Cannula 8 (27.6) 2(6.9) 0.028
Length of IMV 22.9 ± 13.9 - -
Final outcomes
Hospitalisation in ICU 21 (72.4) 1 (3.2) 0.000
Length of hospital stay (days) 40.9 ± 25.3 12.65 ± 7.3 0.000
Exitus 5 (17.2) 2 (6.4) 0.049

Continuous variables are expressed as the mean (±SD). Categorical data are expressed as n (%). ARDS: Acute respiratory distress syndrome. ACE: Angiotensin-converting enzyme. ICU: Intensive care unit. NS: non-significant. IMV: Invasive Mechanical Ventilation. SOFA: Sepsis related Organ Failure Assessment.