Table 1.
Weights, blood pressure, and renal function.
| Groups | C | CKD | CKD + M |
|---|---|---|---|
| Male | N = 8 | N = 8 | N = 8 |
| Body weight (BW) (g) | 360 ± 8 | 261 ± 11 * | 237 ± 8 * |
| Left kidney weight (g) | 1.78 ± 0.07 | 5.1 ± 0.44 * | 4.09 ± 0.27 *# |
| Left kidney weight/100 g BW | 0.49 ± 0.02 | 1.94 ± 0.12 * | 1.73 ± 0.01 *# |
| Systolic blood pressure (mmHg) | 128 ± 1 | 144 ± 1 * | 132 ± 1 # |
| Diastolic blood pressure (mmHg) | 86 ± 1 | 87 ± 1 | 87 ± 2 |
| Mean arterial pressure (mmHg) | 100 ± 1 | 106 ± 1 * | 102 ± 1 |
| Creatinine (μM) | 22.7 ± 1 | 322.7 ± 25.7 * | 235.9 ± 22.4 *# |
| Female | N = 8 | N = 8 | N = 8 |
| Body weight (BW) (g) | 244 ± 11 | 187 ± 6 * | 174 ± 5 * |
| Left kidney weight (g) | 1.12 ± 0.03 | 2.12 ± 0.12 * | 1.91 ± 0.13 * |
| Left kidney weight/100 g BW | 0.46 ± 0.02 | 1.14 ± 0.05 * | 1.09 ± 0.05 * |
| Systolic blood pressure (mmHg) | 118 ± 1 | 132 ± 1 * | 121 ± 1 # |
| Diastolic blood pressure (mmHg) | 75 ± 3 | 84 ± 3 * | 81 ± 1 * |
| Mean arterial pressure (mmHg) | 89 ± 2 | 100 ± 2 * | 94 ± 1 # |
| Creatinine (μM) | 23.4 ± 1.3 | 220.7 ± 23.5* | 190 ± 18.2 * |
* p < 0.05 vs. C; # p < 0.05 vs. CKD.