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. 2021 Jul 28;10(8):1211. doi: 10.3390/antiox10081211

Table 4.

Plasma levels of NO-related parameters.

Groups C CKD CKD + M
Male N = 8 N = 8 N = 8
L-citrulline (µM) 53.7 ± 1.6 47.6 ± 1.1 46.7 ± 1
L-arginine (µM) 165.8 ± 2.8 146.3 ± 4 118.8 ± 1.4 *
ADMA (µM) 1.65 ± 0.02 2.4 ± 0.04 * 1.96 ± 0.05 #
SDMA (µM) 1.21 ± 0.01 1.69 ± 0.04 * 1.61 ± 0.02 *
L-arginine-to-ADMA ratio (µM/µM) 102.4 ± 2.9 66 ± 1.9 * 58.8 ± 1.6 *
Female N = 8 N = 8 N = 8
L-citrulline (µM) 56.1 ± 0.9 53.7 ± 0.8 55.8 ± 1.2
L-arginine (µM) 166.4 ± 2.5 160.9 ± 4.1 140.4 ± 3.2
ADMA (µM) 1.38 ± 0.03 2.1 ± 0.07 * 2.16 ± 0.05 *
SDMA (µM) 1.58 ± 0.07 2.13 ± 0.05 1.72 ± 0.02
L-arginine-to-ADMA ratio (µM/µM) 123.1 ± 3.4 83.2 ± 3.9 * 65.8 ± 1.2 *

* p < 0.05 vs. C; # p < 0.05 vs. CKD.